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Year : 2020  |  Volume : 5  |  Issue : 1  |  Page : 115-120

Role of diffusion-weighted magnetic resonance imaging in detection of neonatal hypoxic-ischemic encephalopathy

1 Department of Diagnostic Radiology, Faculty of Medicine, Assiut University, Assiut, Egypt
2 Department of Radiodiagnosis, Faculty of Medicine, Assiut University, Assiut, Egypt
3 Department of Pediatrics, Faculty of Medicine, Assiut University, Assiut, Egypt

Correspondence Address:
Alaa A Sayed
Department of Radiology, Assiut University, Assiut
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/JCMRP.JCMRP_62_19

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Background Hypoxic-ischemic encephalopathy (HIE) is a critical pediatric disease with challenges in diagnosis. Many diagnostic tools have been used to diagnose this condition. Among all these tools, MRI with the advanced sequence; diffusion-weighted imaging (DWI) plays a more vital role in early detection of this condition. In this research we emphasized the role of DW-MRI in the diagnosis of HIE. Aim of work The aim of this work is to evaluate the role of DW-MRI in detection and grading of HIE. Patients and methods This is a prospective study performed for 1 year (from January 2017 to January 2018). The studied group included 20 full-term neonates admitted to NICU of Assiut University Hospital with provisional diagnosis of HIE. All patients underwent brain imaging by conventional and DW-MRI. Results There was a moderate significant agreement between conventional MRI and DWI (P = 0.023) regarding both diagnosis and grading of HIE. Conclusion MR-DWI is the preferred modality of imaging in diagnosis and grading of hypoxic-ischemic injury due to its high sensitivity and easy interpretation with no need for contrast administration.

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