• Users Online: 111
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
Year : 2020  |  Volume : 5  |  Issue : 1  |  Page : 109-114

Possibility of association of hypertension and ischemic heart disease with primary hyperuricemia

1 Professor of Internal Medicine, Faculty of Medicine, Assiut University, Assuit, Egypt
2 Associate Professor of Internal Medicine Department, Rheumatology and Clinical Immunology Unit Faculty of Medicine, Assiut UniversityInternal Medicine Department, Assuit, Egypt
3 Resident Doctor of Internal Medicine Department, Assuit, Egypt

Correspondence Address:
Sara Mostafa Taher
Department of Internal Medicine, Assuit University, Assuit
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/JCMRP.JCMRP_9_19

Rights and Permissions

Background The relations between serum uric acid and cardiovascular disease are complex, so in the past five decades, more than 40 epidemiologic and clinical studies involving up to 150 000 individuals have been carried out to assess this association. Objective This study aimed to investigate the association between high uric acid levels and cardiovascular disease and hypertension. Patients and methods A total of 40 patients with primary hyperuricemia selected from Internal Medicine Department, Rheumatology Unit, Assiut University Hospital, were included in this study. Age of the studied patients ranged between 23 and 87 years. None of the patients were diabetic, hypertensive, had ischemic heart disease, or were smoker. Moreover, none of them had gout, kidney diseases, or liver cirrhosis. All of the studied patients had normal abdominal ultrasonographic findings with normal urine analysis and normal BMI. Incident hypertension was defined as newly detected blood pressure of at least 140/90 mmHg, which was examined along with ischemic changes by echocardiography. Results Overall, 37.5% patients were discovered to be hypertensive and 32.5% patients had ischemic changes on echocardiography. Conclusion There is a strong and significant association between high uric acid levels and ischemic heart disease and hypertension, and this relationship is independent of traditional risk factors.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded91    
    Comments [Add]    

Recommend this journal